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If your physician has instructed or directed you to take generic for pletal medication in a regular schedule and you have missed a dose of this medicine, take it as soon as you remember.

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Based on its mechanism of actioncilostazol may induce tachycardiapalpitationtachyarrhythmia and/or hypotensionThe increase in heart rate associated with cilostazol is approximately 5 to 7 bpmin patients at risk this consequently may induce angina pectoris.

Caution should be exercised when co-administering cilostazol with any other agents that inhibit platelet aggregationRefer to sections 4.3 and 4.5

Due to cilostazol’s platelet aggregation inhibitory effect it is possible that an increased bleeding risk occurs in combination with surgeryincluding minor invasive measurements like tooth extractionIf a patient is to undergo elective surgery and antiplatelet effect is not necessarycilostazol should be stopped 5 days prior to surgery.

There are no adequate data in the use of cilostazol in pregnant womenStudies in animals have shown reproductive toxicitysee Section 5.3The potential risk for humans is unknownPletal must not be used during pregnancysee section 4.3

Based on its mechanism of actioncilostazol may induce tachycardiapalpitationtachyarrhythmia and/or hypotensionThe increase in heart rate associated with cilostazol is approximately 5 to 7 bpmin patients at risk this consequently may induce angina pectoris.

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